Senior Clinical Fellow in Haematology (CAR-T fellow)

Job overview

University Hospital Southampton NHS Foundation Trust is delighted to offer a fantastic opportunity to work with us.

This is a fixed term contract with the position commencing in the month of September 2025.

Please see below for detailed job description of the role.

Main duties of the job

This is a replacement appointment for a CAR-T fellow in Haematology, based at Southampton General Hospital.

The post has been developed to support the CAR-T cell programme, working closely with the Southampton Lymphoma Service and the Wessex Bone Marrow Transplantation and Cell Therapy Program (WBMT&CTP).

You will join the Department of Clinical Haematology and participate in the management of patients with haematological disorders undergoing CAR-T cell therapy (including ALL, Lymphoma and other indications as they arise). You will work within consultant-led subspecialty teams, alongside specialty registrars. There may be the option to contribute to the haematology on-call rota depending on experience and needs of the service.

Whilst the post is ideally suited to a haematology specialty trainee or equivalent, the post is open to individuals with at least MRCP Part 2, higher speciality qualification, or equivalent.

The posts can be tailored to fit the your needs, including if you're post-CCT or have undertaken haematology training oversees or wish to obtain specific subspecialty experience. You will be exposed to cell-therapy clinical trial activity, and research opportunities will be available.

Detailed job description and main responsibilities

Southampton has a comprehensive research active Clinical Haematology department, incorporating Haematological Oncology, Stem Cell Transplantation and Cellular Therapy, Transfusion Medicine, Haemoglobinopathies, General and Immune Haematology and Haemostasis & Thrombosis services. The Haematology service is subspecialty based and provides clinical and laboratory service both to the local population in Southampton and South West Hampshire, as well as tertiary referrals for specialist opinions for complex cases and for a range of clinical trials.

The principal duties of the posts will include:

• Review of patients referred for CAR-T cell therapy, in an outpatient or inpatient setting.
• Liaison with referring teams, CAR-T consultants, and CAR-T coordination team in planning for apheresis, bridging, infusion, discharge, and post-CAR-T follow-up.
• Management of patients undergoing CAR-T cell therapy in the inpatient and ambulatory setting, in collaboration with the subspecialty teams and supervising CAR-T consultants.
• Referral to other specialty teams (e.g. intensive care, neurology, cardiology) as required to provide optimal care of patients undergoing CAR-T cell therapy.
• Discussion of cases as appropriate at the Southampton lymphoma and leukaemia/myeloma MDTs, and the CAR-T MDT.
• Active involvement with the development and expansion of the CAR-T service within the WBMT&CT, in collaboration with the subspecialty CAR-T leads.
• Active involvement in the recruitment and management of patients within CAR-T clinical trials
• Collaboration with other colleagues in the region through MDT and network-wide working
• Development of regional CAR-T referral pathways in collaboration with CAR-T lead consultants
• Participation in clinical governance activities including morbidity and mortality meetings and other committees as appropriate both within and external to the department.
• Contribution to the audit activities of the WBMT&CT Programme and wider haematology department, including specialty regional and national audit programmes. Where possible, to participate in the collection and analysis of local data with a view to preparing and submitting papers for publication, and to contribute to the ongoing collection of ‘real-world’ UK CAR-T data through the National CAR-T Clinical Panel (NCCP).
• Undertaking of procedures relevant to haematology, including bone marrow biopsy, intrathecal chemotherapy, and tunnelled central catheter removal. Where necessary, appropriate training and supervision will be provided.
• Engagement with the education programme, including attendance at regular educational meetings. Pre-CCT post-holders will be expected to maintain an educational portfolio mirroring their equivalent stage of training. Post-CCT fellows will be required to engage with the trust’s existing appraisal system.
• Cross-cover to other specialty teams within haematology during both planned and unplanned absence.

Education and Training Opportunities:

The haematology education and training programme was overhauled in 2021 following the launch of the JRCTB Haematology Curriculum. You will have access to the same training opportunities as the Specialist Registrars including being allocated an educational supervisor, study leave and self-development time.

There is a weekly Wessex-wide teaching programme encompassing clinical and laboratory haematology plus specific laboratory morphology sessions for more junior trainees to gain laboratory competencies. There are several regional training days each year.

There will be opportunity to take on Quality Improvement Projects and other clinical research activities dependent on your interests.

ADDITIONAL INFORMATION

Appointment will be made under local contractual terms and conditions of service for Trust appointed (non-training fellow doctors and dentists).     Successful candidates will have an educational framework equivalent to training grade doctors, and there will be a named educational supervisor assigned at the start of the post. The opportunity for Continued Professional Development (CPD) is highly supported and encouraged by the Trust, with options available to take study leave. All licensed doctors must meet the GMC requirements for revalidation and there will be an annual appraisal to support this process.    Grades for Trust appointed (non-training) fellows will be paid a basic salary at a nodal pay point linked to the grade, at the rate set out in the National Medical and Dental pay circular.   Basic salary detailed below plus any additional remuneration (as applicable) for hours set out in the doctors work schedule (e.g. additional hours, weekend allowance, and any hours which attract enhanced pay)

Basic Salary – MT04  £65,048      Basic Salary – MT05 £73,992

Salary will be assessed based on experience and skills. Eligibility criteria for appointment to a Nodal Point 5;

• Have a minimum of 6 years of Specialty training     •    Hold relevant higher specialty exam (e.g FRCP, FRCA, FRCS)  •    A portfolio of evidence that demonstrates they meet the criteria for progression (in line with the Curriculum for the speciality similar to deanery trainee)

Travelling expenses will not be paid for attending interview  Please note that GMC registration (with a licence to practice) and right to work in the UK are essential for this role.

Successful applicants will already have GMC registration or will be able to demonstrate they are eligible.

Applicants requiring Tier 2 sponsorship should ensure they meet the Home Office application criteria prior to submitting an application.

Interviews will be held on 8th August 2025

Job Reference; 188-MB10725- This vacancy closes on or before 29th July 2025