Clinical Research Fellow

Job overview

The post holder will be responsible for assisting and leading on the running of multicentre randomised controlled trials within Skeletal Dysplasia. This will involve the use of a novel drugs and devices. You will work as part of and be supported by a multi-disciplinary research team with a strong track record of producing high impact, translational research.

The post will be based at St Thomas’. However, it is a requirement that you be prepared to work at any additional or different location owned or served by the Trust, either on an on-going or temporary basis according to the demands of the service.

Main duties of the job

You will coordinate and lead research projects as a sub-investigator, recruit and follow up patients according to trial protocols, collect and analyse clinical data, maintain trial documentation, and contribute to publications and presentations. The role also includes participation in specialist clinics and close collaboration with principal investigators and wider research teams.

Detailed job description and main responsibilities

Duties and Responsibilities:

• Conducting baseline assessment and follow up of patients as per the trial protocol
• Involved with clinical care of patients who consent to take part in the trials.

• Review undiagnosed 100 000 Genomes Project patients with skeletal dysplasia and liaise with the Musculoskeletal Genomics England Interpretation partnership (MSK GECIP) to close open cases
• Co-ordinate and lead on research projects as sub-investigator
• Recruit patients
• Collect data and help maintain trial documentation
• Ensure governance procedures are followed
• Observe and assist in the multidisciplinary skeletal dysplasia and achondroplasia clinics
• Data analysis, presentation and drafting of manuscripts
• Participate in clinical activities with object of ensuring high standard of patient care
• Work closely with the Principal Investigator(s) to be responsible for ensuring that the research components of the project are carried out in a timely and effective way
• Liaise closely with colleagues in the research area, including those working on their own and other projects
• Review relevant literature and reporting on work by others in related areas
• Ensure appropriate ethical clearance is obtained for all research activity and any study amendments
• Write progress reports
• Present findings to different audiences and attend relevant conferences

Communication & networking:

• Communicate material of a specialist and complex nature using a range of media, within your own discipline and with colleagues from other disciplines
• Interact with local collaborators and oversee the data flow to these where appropriate
• Assimilate the language and thinking of other disciplines to facilitate effective collaboration with multidisciplinary teams
• Assist in organising regular project planning meetings with research teams in addition to attending group meetings organised by others
• Work closely with other academics and Laboratory and Facility managers
• Keep colleagues informed of developments in the research literature
• Keep the Laboratory Manager and supervisors informed of any problems with equipment and laboratories.
• Good general communication skills are essential for recruitment of and interaction with study patients and for the interaction with clinical and research staff
• Develop essential, positive working relationships with referring clinicians
• Decision making, planning & problem solving
• Assist staff compiling regulatory documentation
• Develop and disseminate guidelines resulting from problem resolution
• Plan and act independently to take forward assigned projects and discuss these with the research teams
• Working independently with only low-level supervision
• Assist and advise junior researchers and students in the planning and execution of their research

Service delivery:

• Assist in monitoring progress to achieving the objectives of the research
• Support other members of the team
• Adopt systems of work as required by the Local Rules
• Comply with Divisional, Faculty and Trust wide policies and regulations

*** Please be advised that this vacancy may close early should we receive sufficient number of applications ***