Clinical Research Fellow in Gastroenterology

Job overview

Applicants are invited to apply for the position of Clinical Research Fellow in IBD / Gastroenterology, based at Imperial College Healthcare NHS Trust and Imperial College London.

The appointee will be involved in a research project under the supervision of Dr. James Alexander and Prof. Nick Powell. This is an excellent opportunity for individuals with an interest in Inflammatory Bowel Disease (IBD) research and they will be expected to register for a higher degree (MD or PhD).

A degree in Medicine (MBBS or equivalent) and full MRCP or equivalent is essential, as is full General Medical Council registration.  You will have minimum experience as an ST4 in Gastroenterology.

Main duties of the job

The research project is fully funded by a grant from GlaxoSmithKline to deliver a multicentre interventional trial of the recombinant zoster vaccine (Shingrix) in patients with IBD. The trial aims to determine if pausing IBD medication during immunisation results in enhanced immunological responses to vaccination. The appointee will support the Imperial Clinical Trials Unit with patient recruitment and lead on laboratory analysis of antibody and cell-mediated immunity. The position will provide opportunities and training to employ cutting edge translational science, including gut microbiome and metabolomic platforms, to understand variability in vaccination responses. And the project will also leverage UK-wide collaborative networks to explore the critical issue of vaccination hesitancy in patients with IBD. It is anticipated that the results of the project will be presented at national and international meetings, and published in high-impact peer-reviewed journals.

Detailed job description and main responsibilities

The appointed candidate will help manage patients with acute and chronic gastrointestinal disease (such as inflammatory bowel disease, gastrointestinal haemorrhage, gastrointestinal infection and cancer, motility and functional disorders) along with patients with general medical problems.

The post holder will be required to provide the clinical support and knowledge required for the day-to-day delivery of the OVATION-IBD trial. You will have a good understanding of IBD and a good understanding of trial methodology. You will be able to interpret findings and demonstrate understanding and limitations of study design and available data.