# CRF Senior Clinical Research Nurse > NHS job listing from Job Clerk for Guy's and St Thomas' NHS Foundation Trust. ## Canonical URLs - **HTML:** https://www.jobclerk.com/job/crf-senior-clinical-research-nurse/9c9bc9fb-461b-4941-beba-730161265a4b - **Markdown:** https://www.jobclerk.com/job/crf-senior-clinical-research-nurse/9c9bc9fb-461b-4941-beba-730161265a4b.md ## Summary - **Status:** Live - **Employer:** Guy's and St Thomas' NHS Foundation Trust - **Location:** St Thomas' Hospital - **Workplace type:** onsite - **Profession:** Nurse (adult and children) - **Grade:** Band 7 - **Salary:** £58,133 - £65,261 p.a. inc HCA - **Contract type:** Permanent - **Employment type:** Full time - 37.5 hours per week (Work patterns will include day shifts, late shifts, and some night duties as required by trial protocols.) - **Closing date:** 2026-09-13T22:59:00.000Z - **Posted:** 2026-08-28T18:01:25.502Z - **Source information URL:** https://www.healthjobsuk.com/job/UK/London/London/Guys_St_Thomas_NHS_Foundation_Trust/CRF_Senior_Clinical_Research_Nurse/CRF_Senior_Clinical_Research_Nurse-v8258984 - **Application URL:** https://apps.trac.jobs/job-advert/8258984?ShowJobAdvert=&feedid=9002 - **Employer website:** https://www.guysandstthomas.nhs.uk ## Job Content ### Job overview We are looking for an exceptional senior research nurse to join the clinical research facility (CRF) research team. This post will provide clinical leadership for our expanding research portfolio, manage junior research delivery staff and support the team to deliver high-quality research. You will be responsible for the management of your team's research portfolio, reviewing protocols, amendments and identifying resource implications. You will have line management responsibilities and will actively be involved with staff recruitment, training, supporting and mentoring of all team members. Applicants must be a registered adult nurse with evidence of continuing professional development. You should have good experience in clinical research within the NHS, a strong clinical background and desire and willingness to learn and develop others. Essential skills are excellent communication and interpersonal skills, the ability to prioritise and meet tight deadlines, the ability and initiative to work independently and manage a patient caseload across a variety of research studies. The post holder is expected to work on shift patterns necessary to ensure patient safety and timely delivery of clinical trials. Work patterns will include day shifts, regular late and some night duties and weekends as required by trial protocols. ### Main duties of the job Responsibilities will include the co-ordination of a portfolio of early phase translational clinical research, collaborating with key personnel throughout the two adult Clinical Research Facilities (CRF), to ensure continued care and support for patients and healthy volunteers involved in these clinical trials and studies. The post holder will take responsibility for supervising the safe administration of experimental therapies, and for monitoring the effects of drugs and other treatment modalities used in these trials. They may also be involved in gaining ethical approval, collecting data, interviewing and data entry. The post holder will be expected to advocate for patients and empower them to make informed choices concerning their involvement in the clinical trials by providing advice and information. The post holder will be involved in improvement projects to further develop the operational aspect of the CRFs. This includes attending feasibility and initiation meetings, monitoring CRF supplies and equipment, facilitating orientation and support of external staff to the CRF. Aspects of the role will include clinical tasks such as phlebotomy, analysis of blood specimens, drug administration and clinical observation. The post holder will work with a high level of autonomy, taking delegated responsibility from Clinicians for clinical decision making, and will work closely with the Investigator and multidisciplinary staff. ### Detailed job description and main responsibilities The post holder will: - Lead on participant communications and well-being issues, providing specialist advice relevant to clinical research nursing - Be responsible for leading a research nurse team to support screening of eligible research participants including providing information and support to participants, clinical follow-up, data collection and safety reporting according to requirements - Work with the CRF Matron to establish and maintain key strategic relationships with networks of clinicians, researchers and health service managers for effective roll-out of the trials - Work alongside a team of trial coordinators, data managers and database developers to ensure compliance with GCP, data protection and research governance frameworks, regulations and sponsor requirements - Support the development of training materials for clinical research staff at study sites including study specific and informed consent training and elements of GCP - Monitor participants’ experience and identify important participants’ well-being issues - Be a central point of contact for site staff for trial-specific procedures including support to participants, eligibility assessment, informed consent, and sample management. ### Applicant requirements You must have appropriate UK professional registration. This post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service. ## Person Specification ### Skills **Essential** - Substantial experience in clinical trials, teaching and mentoring as demonstrated by your individual portfolio. - Knowledge and understanding of current UK clinical trial regulations, good clinical practice and the Declaration of Helsinki 1996 - Experience delivering specialised programmes of care, and provide highly specialised advice for patients and healthy volunteers who are participating in clinical trials - Experience facilitating and undertaking R&D activities as major job component and undertake research, lead clinical audit in own area. - Knowledge and experience of handling complex relationships - Demonstrable managerial/ team leader experience - Experience of mentoring and developing staff - Experience of collaborating with other agencies **Desirable** - Experience of planning and delivery of training and associated resources ### Experience **Essential** - Able to provide and receive complex, sensitive information, communicating this highly sensitive information to patients using empathy and reassurance, gain cooperation where required and overcome barriers to understanding by possessing excellent communication and interpersonal skills - Able to plan and organise complex activities and programmes, requiring formulation and adjustment as necessitated - You will recruit to, support and develop a specialist nursing service provision - You will have the dexterity and coordination needed for undertaking venepuncture, intramuscular, skin punch biopsies and accuracy required for e.g. intravenous injections, syringe pumps and infusions - You will possess basic laboratory skills such as centrifugation and sample separation - You will be able to teach/deliver core training of individual clinical trial/study protocols to junior members of staff - Excellent communication and interpersonal skills - Ability to work autonomously and as a member of a small team, as well as part of the wider multidisciplinary team - Ability to set direction and lead a team of research professionals - Ability to work across boundaries, integrating with multidisciplinary staff in relation to research trials **Desirable** - SACT accreditation ### Knowledge/Qualifications **Essential** - NMC Level One Registration – RN Adult - Your professional knowledge acquired at degree level will be supplemented by specialist training, experience and/or short courses - ICH GCP certificated ## Documents - [job description (pdf, 432.6kb)](https://www.healthjobsuk.com/documents?vdoc=10572433) - [person specification (pdf, 552.3kb)](https://www.healthjobsuk.com/documents?vdoc=10577841) - [crf senior clinical research nurse frf apr 2026 (pdf, 241.8kb)](https://www.healthjobsuk.com/documents?vdoc=10572575) ## Agent Notes - This Markdown page is generated from the same Job Clerk job record as the HTML job detail page. - Use the canonical HTML URL for user-facing references. - Use the application URL when the user wants to apply on the source NHS site.