# Clinical Scientist > NHS job listing from Job Clerk for Great Ormond Street Hospital for Children NHS Foundation Trust. ## Canonical URLs - **HTML:** https://www.jobclerk.com/job/clinical-scientist/0f027cef-260e-44d7-ac29-88798052ba68 - **Markdown:** https://www.jobclerk.com/job/clinical-scientist/0f027cef-260e-44d7-ac29-88798052ba68.md ## Summary - **Status:** Live - **Employer:** Great Ormond Street Hospital for Children NHS Foundation Trust - **Town:** London - **Region:** London - **Country:** England - **Profession:** Health science services - **Grade:** Band 7 - **Salary:** £58,133 - £65,261 Inclusive per annum - **Contract type:** Permanent - **Employment type:** Full time - 37.5 hours per week - **Closing date:** 2026-07-12T23:59:00.000Z - **Posted:** 2026-06-25T09:13:13.289Z - **Source information URL:** https://www.healthjobsuk.com/job/UK/London/London/Great_Ormond_Street_Hospital_Children_NHS_Foundation_Trust/Genomics/Genomics-v8038200 - **Application URL:** https://apps.trac.jobs/job-advert/8038200?ShowJobAdvert=&feedid=9002 - **Employer website:** https://www.gosh.nhs.uk ## Job Content ### Job overview Applications are invited from State Registered Clinical Scientists in Genomics. Scientists close to registration will also be considered. You will be joining the team at the North Thames Rare Disease Genomics Laboratory at Great Ormond Street Hospital. We are seeking enthusiastic, self-motivated Scientists with experience of clinical genomics service delivery and a sound understanding of genomic techniques including variant assessment. Accomplished communication and organisational skills are required. You will support an area of our core, specialist or prenatal genomics service dependent on experience.  Applications are welcome from registered scientists from either cytogenetics or molecular genetics.  Our scientific teams are cross-discipline with opportunities for cytogenetics and molecular genetics across the department.  We support trained scientists who wish to adopt flexible and/or partially remote working patterns. ### Main duties of the job The GOSH Genomics Laboratory has an establishment of approximately 180 including Technologists, Clinical Scientists, Translational Scientists, Bioinformaticians and Administrative Support staff. Along with two Clinical Genetics Teams we form a strategic Genetics Unit within the hospital and provide North London with a Regional Genetics Service serving a population of approximately 10 million.  The laboratory provides an in-house diagnostic service for paediatric  and inherited cancer, molecular and cytogenetic testing in accordance with the NHS England Genomic Test Directory; this includes services for 11 of the designated specialist areas for the NHSE Genomic Medicine Service. Genomic testing is provided for both prenatal and postnatal samples using SNP microarray, karyotyping, FISH, qPCR, MLPA, Next generation sequencing, rapid genome sequencing, and various targeted tests. We are also engaged in the delivery of the NHSE GMS Whole Genome Sequencing programme for our North Thames patients. We are involved in a number of collaborative research and development projects with colleagues at the UCL Institute of Child Health and Institute of Neurology as part of the UCL Partners Academic Health Sciences Centre.  We host a team of Translational and Research Scientists focusing on translation of new genomic technologies to the diagnostic service. ### Detailed job description and main responsibilities The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below. ## Job Details Applications are invited from State Registered Clinical Scientists in Genomics. Scientists close to registration will also be considered. You will be joining the team at the North Thames Rare Disease Genomics Laboratory at Great Ormond Street Hospital. We are seeking enthusiastic, self-motivated Scientists with experience of clinical genomics service delivery and a sound understanding of genomic techniques including variant assessment. Accomplished communication and organisational skills are required. You will support an area of our core, specialist or prenatal genomics service dependent on experience. Applications are welcome from registered scientists from either cytogenetics or molecular genetics. Our scientific teams are cross-discipline with opportunities for cytogenetics and molecular genetics across the department. We support trained scientists who wish to adopt flexible and/or partially remote working patterns. ## Job Description The GOSH Genomics Laboratory has an establishment of approximately 180 including Technologists, Clinical Scientists, Translational Scientists, Bioinformaticians and Administrative Support staff. Along with two Clinical Genetics Teams we form a strategic Genetics Unit within the hospital and provide North London with a Regional Genetics Service serving a population of approximately 10 million. The laboratory provides an in-house diagnostic service for paediatric and inherited cancer, molecular and cytogenetic testing in accordance with the NHS England Genomic Test Directory; this includes services for 11 of the designated specialist areas for the NHSE Genomic Medicine Service. Genomic testing is provided for both prenatal and postnatal samples using SNP microarray, karyotyping, FISH, qPCR, MLPA, Next generation sequencing, rapid genome sequencing, and various targeted tests. We are also engaged in the delivery of the NHSE GMS Whole Genome Sequencing programme for our North Thames patients. We are involved in a number of collaborative research and development projects with colleagues at the UCL Institute of Child Health and Institute of Neurology as part of the UCL Partners Academic Health Sciences Centre. We host a team of Translational and Research Scientists focusing on translation of new genomic technologies to the diagnostic service. ## Responsibilities The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below. ## Person Specification ### Combined Values **Essential** - Combined Values ### Skills/Abilities **Essential** - Skilled in the use and application of molecular genetics and/or cytogenetic techniques - Skilled in genomic CNV analysis by use of G banded chromosomes / FISH / Microarray OR Skilled in Next Generation Sequencing Applications / Sanger Sequencing / Dosage analysis - Able to establish and validate new techniques / tests including ability to troubleshoot. Willing to adapt to changes in methodology - Computer literate, including use of DNA/Genetic databases, analytical software, variant classification - Able to communicate effectively both verbally and in writing (by email and by appropriate documentation) - Able to write protocols ### Experience/Knowledge **Essential** - Extensive knowledge of clinical genomics and a demonstrable track record in the delivery of a diagnostic service - Knowledge of structural chromosome rearrangements and segregation, CNV analytical methods and clinical applications OR - Knowledge and experience of molecular variant classification in accordance with ACGS guidance and their application for all modes of inheritance - Track record of scientific Publications/ presentations - Significant postgraduate experience in a clinical genomics laboratory **Desirable** - Evidence of supervising/training other staff - Experience with laboratory information and quality management systems ### Academic/Professional qualification/Training **Essential** - First or Second Class Degree in Molecular Biology, Genetics, Biochemistry or related subject - HCPC Clinical Scientist Registration Certificate **Desirable** - Postgraduate qualification in Genomics ## Documents - [job description (pdf, 681.1kb)](https://www.healthjobsuk.com/documents?vdoc=10405158) - [staff benefits leaflet (pdf, 108.2kb)](https://www.healthjobsuk.com/documents?edoc=2815) - [diversity and inclusion (pdf, 166.5kb)](https://www.healthjobsuk.com/documents?edoc=2485) ## Agent Notes - This Markdown page is generated from the same Job Clerk job record as the HTML job detail page. - Use the canonical HTML URL for user-facing references. - Use the application URL when the user wants to apply on the source NHS site.